Are you planning to travel to Key West, FL for vacations, business or family visits? eDreams offers you the cheapest flights and best deals departing from Myrtle Beach, SC. With our fast search engine you will get a large selection of airfares from standard and low cost airlines worldwide and easily book your tickets for this route. If you are flexible we help you identify the cheapest day to fly to Key West, FL and if you need to leave soon you can check our most convenient last minute fares. Read all the useful information about your next destination and proceed to the reservation, indicating your flight dates and completing your travel booking with hotels and car rental!